Human-GDNF, rec.

10 µg

Recombinant Human Glial-derived Neurotrophic Factor (GDNF) produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 2 x 135 amino acids and having a total molecular mass of 30,360 Dalton.

This factor was found initially in conditioned medium of the rat B49 glial cell line.GDNF is a disulfide-bonded homodimeric glycosylated protein of 134 amino acids .The proteins contain seven conserved cysteine residues in the same relative spacing found in all members of the TGF-beta superfamily of proteins. Related factors are Neurturin , Persephin , and Artemin . Collectively they are being referred to as GDNF family ligands. ProSpec's Glial-Derived Neurotrophic Factor is fully biologically active when compared to standard. The ED50, calculated by the dose-dependant dopamin uptake in rat mesencephalic cultures was found to be 5-10 ng/mL.

Productnumber: C4303.0010

Productdetails:

  Human-GDNF, rec. 10 µg

Application: cytokines and growth factors used in cell culture application

Source: Escherichia Coli.

Technical Data: Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) GDNF.

Shipping/Storing-Information: shipped at RT, store at -20°C

Deutsche Produktseite:
Human-GDNF, rec. 10 µg  Antibodies & Cytokines

Matchcode: Glial cell line-derived neurotrophic factor precursor Astrocyte-derived trophic factor 1 ATF-1 GDNF