Human flt3-ligand, rec.

2 µg

Recombinant Human Flt3-Ligand produced in E.Coli is non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17605 Dalton.

This ligand binds to Fms-Like Tyrosine Kinase-3 (FLT-3).Human FLT3 ligand also stimulates the proliferation of cells expressing murine FLT-3 receptors. The effects of FLT-3 ligand are synergized by coexpression of G-CSF , GM-CSF , M-CSF , IL3 and SCF . FLT-3 ligand promotes long-term expansion and differentiation of human pro-B-cells in the presence of IL7 or in combination of IL7 and IL3 . rHuFlt3-Ligand is fully biologically active when compared to standard. The ED50, calculated by the dose-dependant stimulation of the proliferation of human AML5 cells is less then 1.0 ng/mL, corresponding to a specific activity greater then 1 x 10(6) units/mg.

Productnumber: C4300.0002

Productdetails:

  Human flt3-ligand, rec. 2 µg

Application: cytokines and growth factors used in cell culture application

Source: Escherichia Coli.

Technical Data: Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) FLT-3.

Shipping/Storing-Information: shipped at RT, store at -20°C

Deutsche Produktseite:
Human flt3-ligand, rec. 2 µg  Antibodies & Cytokines

Matchcode: SL cytokine precursor (Fms-related tyrosine kinase 3 ligand) Flt3ligand Flt3L