rHuAcrp30 HEK 1 mg

Recombinant Human Adiponectin glycosilated, HEK293 cell line. Synonyms: Acrp30, AdipoQ, GBP-28, APM-1, ACDC.

Adiponectin is a recently discovered 244 amino acid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells (Adipokine). The protein belongs to the soluble defense collagen super family; it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. APM-1 forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. The Acrp30 Human Recombinant is fused with a FLAG tag. In vitro gluconeogenesis assay in primary hepatocytes was performed, showing the Adiponectin human derived from mammalian cells can inhibit glucose production. The ED50 was ca. 6µg/mL.