rHuIL-7 Yeast 2 µg

Recombinant Human Interleukin-7 Saccharomyces derived. Synonyms: Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7.

Rec. human Interleukin-7 produced in yeast is a single, glycosylated polypeptide chain of 152 amino acids and a molecular mass of 17.4kDa. IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival.