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rHuVEGF CHO

1 mg

Recombinant Human Vascular Endothelial Growth Factor-CHO

4961,25 € (EUR)

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Recombinant Human VEGF produced in CHO cells is a double, glycosylated, polypeptide chain of 165 amino acids that migrates at ca. 44 kDa in SDS-PAGE under non-reducing conditions. Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Synonyms: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.

rHuVEGF CHO 1 mg - C6387.1000

rHuVEGF CHO 1 mg - C6387.1000

Productnumber: C6387.1000

Deutsch rHuVEGF CHO 1 mg
Antikrper & Zytokine

Source: CHO cells

Technical Data: Purity: >97% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rHuVEGF is soluble in water and most aqueous buffers above the isoelectric point. Endotoxin: Less than 0.1 ng/g (IEU/g) rHuVEGF. Amino acid sequence: APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR.

Shipping/Storing-Information: shipped at RT, stored at -20C

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pdf rHuVEGF CHO 1 mg

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pdf rHuVEGF CHO 1 mg

Matchcode: Recombinant Human Vascular Endothelial Growth Factor-CHO