rec. Human Erythropoetin-alpha (rHuEPO-a) 50 µg

The protein was frozen after extensive dialysis in 5.8 mg sodium citrate, 5.8 mg sodium chloride and 0.06 mg citric acid.

Recombinant Human EPO-a is produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology as a single, polypeptide chain of 165 amino acids and a predicted molecular mass of 21,000 Dalton and apparent glycosylated molecular mass of 30,400 Dalton. This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. Synonyms: Erythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, MGC138142.