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rec. Human Interleukin-1 Receptor Antagonist (rHuIL-1 ra)

1 mg

Lyophilized protein without additives. IL-1 ra is fully biologically active when compared to standard. The ED50 as determined by the dose-dependant inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/mL.

1030,00 € (EUR)

plus 19% VAT and
shipping costs

Synonyms: IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430. Recombinant Human IL-1 ra produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain of 153 amino acids and a molecular mass of 17,000 Dalton. Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

rec. Human Interleukin-1 Receptor Antagonist (rHuIL-1 ra) 1 mg -

rec. Human Interleukin-1 Receptor Antagonist (rHuIL-1 ra) 1 mg -

Productnumber: C6013.1000

Deutsch rec. Human Interleukin-1 Receptor Antagonist (rHuIL-1 ra) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 99.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rHuIL-1 ra is soluble in water and most aqueous buffers below and above the isoelectric point. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rHuIL-1 ra.

Shipping/Storing-Information: shipped at RT, stored at -20°C

Productdetails:


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Matchcode: Interleukin-1 Receptor Antagonist rHuIL-1 ra