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rec. Human Interleukin-7 (rHuIL-7)

1 mg

Lyophilized from a concentrated (1 mg/mL) solution in water containing no additives. Synonyms: Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7.

5092,50 € (EUR)

plus 19% VAT and
shipping costs

Recombinant Human IL-7 produced in E.Coli is a single, non-glycosylated polypeptide of 172 amino acids and a molecular mass of 17,412 Dalton. The ED50 as determined by the dose-dependant stimulation of murine IXN/2B cells is <0.3 ng/mL, corresponding to a Specific Activity of 1 x 10(6) IU/mg. IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival.

rec. Human Interleukin-7 (rHuIL-7) 1 mg - C6027.1000

rec. Human Interleukin-7 (rHuIL-7) 1 mg - C6027.1000

Productnumber: C6027.1000

Deutsch rec. Human Interleukin-7 (rHuIL-7) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: >98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Sterile Filtered White lyophilized (freeze-dried) powder. Lyophilized from a concentrated (1mg/mL) solution in water containing no additives. The ED50 as determined by the dose-dependant stimulation of murine IXN/2B cells is <0.5ng/mL, corresponding to a Specific Activity of 2,000,000 IU/mg.

Shipping/Storing-Information: shipped at RT, stored at -20°C

Documentation:


pdf rec. Human Interleukin-7 (rHuIL-7) 1 mg

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pdf rec. Human Interleukin-7 (rHuIL-7) 1 mg

Matchcode: Interleukin-7 rHuIL-7