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rec. Human Stem Cell Factor (rHuSCF)

1 mg

Lyophilized from a concentrated (1 mg/mL) solution in water containing 10 mM acetic acid.

3375,00 € (EUR)

plus 19% VAT and
shipping costs

Recombinant Human SCF produced in E.Coli is a single, non-glycosylated polypeptide chain of 164 amino acids and a molecular mass of 18,409 Dalton. The ED50 as determined by the dose-dependant stimulation of Human TF-1 cells is <2ng/mL, corresponding to a Specific Activity of 5 x 10(5) IU/mg. Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as ""steel factor"" or ""c-kit ligand"". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid). Synonyms: Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250.

rec. Human Stem Cell Factor (rHuSCF) 1 mg - C6055.1000

rec. Human Stem Cell Factor (rHuSCF) 1 mg - C6055.1000

Productnumber: C6055.1000

Deutsch rec. Human Stem Cell Factor (rHuSCF) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 99.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rHuSCF is soluble in water and most aqueous buffers above the isoelectric point. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rHuSCF.

Shipping/Storing-Information: shipped at RT, stored at -20°C

Documentation:


pdf rec. Human Stem Cell Factor (rHuSCF) 1 mg

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pdf rec. Human Stem Cell Factor (rHuSCF) 1 mg

Matchcode: Stem Cell Factor rHuSCF