IndexAntibodies & CytokinesCytokines & Growth F.

Deutsch

rec. Human Tumor Necrosis Factor alpha (rHuTNF-a)

1 mg

Synonyms: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2. Lyophilized from a concentrated (1mg/mL) solution with 5mM Tris pH8.0.

1752,55 € (EUR)

plus 19% VAT and
shipping costs

Recombinant Human TNF-a produced in E.Coli is a single, non-glycosylated, polypeptide chain of 158 amino acids and a molecular mass of 17,483 Dalton. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is <0.05ng/mL, corresponding to a Specific Activity of 2.2 x 10(7) IU/mg. Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.

rec. Human Tumor Necrosis Factor alpha (rHuTNF-a) 1 mg - C6041.1

rec. Human Tumor Necrosis Factor alpha (rHuTNF-a) 1 mg - C6041.1

Productnumber: C6041.1000

Deutsch rec. Human Tumor Necrosis Factor alpha (rHuTNF-a) 1 mg
Antikrper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 99.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/g (IEU/g) rHuTNF-a.

Shipping/Storing-Information: shipped at RT, stored at -20C

Documentation:


pdf rec. Human Tumor Necrosis Factor alpha (rHuTNF-a) 1 mg

Productdetails:


pdf rec. Human Tumor Necrosis Factor alpha (rHuTNF-a) 1 mg

Matchcode: Tumor Necrosis Factor alpha rHuTNF-a