rec. Murine Granulocyte Macrophage Colony Stimulating Factor (rmGM-CSF)
Lyophilized after extensive dialysis against 10mM acetic acid buffer pH=4.0. Synonyms: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim.
2975,00 € (EUR)
Recombinant murine GM-CSF produced in E.Coli is a single, non-glycosylated, polypeptide chain of 125 amino acids and a molecular mass of 14,285 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of murine FDC-P1 cell line is <0.2ng/mL, corresponding to a Specific Activity of 5,000,000 IU/mg. GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Synonyms: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim.
rec. Murine Granulocyte Macrophage Colony Stimulating Factor (rm
rec. Murine Granulocyte Macrophage Colony Stimulating Factor (rmGM-CSF) 1 mg
Antikörper & Zytokine
Source: Escherichia Coli.
Technical Data: Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rmGM-CSF is soluble in water and most aqueous buffers above the isoelectric point (pI=5.96). Endotoxin: Less than 0.1ng/µg (IEU/µg) rmGM-CSF.
Shipping/Storing-Information: shipped at RT, stored at -20°C
Matchcode: Granulocyte Macrophage Colony Stimulating Factor rmGM-CSF