IndexAntibodies & CytokinesCytokines & Growth F.

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rec. Rat Insulin-Like Growth Factor I (rrlGF-I)

1 mg

Recombinant Rat IGF- produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7687 Dalton.

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The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003). Rec. Insulin-Like Growth Factor from rat produced in E.Coli is a single, non-glycosylated, polypeptide chain of 70 amino acids and a molecular mass of 7687 Dalton. Synonyms: Somatomedin C, IGF-I, IGFIA, IGF1. Rat IGF-1 is fully biologically active when compared to standards. The ED50, was calculated 2 methods: 1. Stimulation of protein synthesis in rat L6 myoblasts ED50 was found to be less then 30 ng/mL. 2. Type 1 IGF receptor binding assay ED50 was found to be less then 10 ng/mL.

rec. Rat Insulin-Like Growth Factor I (rrlGF-I) 1 mg - C6074.100

rec. Rat Insulin-Like Growth Factor I (rrlGF-I) 1 mg - C6074.100

Productnumber: C6074.1000

Deutsch rec. Ratten Insulin-Like Growth Factor I (rrlGF-I) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 95.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rrIGF-1.

Shipping/Storing-Information: shipped at RT, stored at -20°C

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