IndexAntibodies & CytokinesCytokines & Growth F.

Deutsch

rec. Rat Interleukin-15 (rrIL15)

1 mg

Recombinant Rat IL-15 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 115 amino acids and having a molecular mass of 13533 Dalton.

3800,00 € (EUR)

plus 19% VAT and
shipping costs

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. Rec. Interleukin-15 Rat produced in E.Coli is a single, non-glycosylated polypeptide chain of 115 amino acids and a molecular mass of 13533 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <10ng/mL, corresponding to a Specific Activity of 100,000IU/mg.

rec. Rat Interleukin-15 (rrIL15) 1 mg - C6078.1000

rec. Rat Interleukin-15 (rrIL15) 1 mg - C6078.1000

Productnumber: C6078.1000

Deutsch rec. Ratten Interleukin-15 (rrIL15) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rrIL-15.

Shipping/Storing-Information: shipped at RT, stored at -20°C

Documentation:


pdf rec. Rat Interleukin-15 (rrIL15) 1 mg

Productdetails:


pdf rec. Rat Interleukin-15 (rrIL15) 1 mg

Matchcode: rec. Rat Interleukin-15 (rrIL-15) Ratteninterleukin-15