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rec. Rat Interleukin-18 (rrIL-18)

1 mg

Recombinant Rat IL-18 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids and having a molecular mass of 18260 Dalton.

4961,25 € (EUR)

plus 19% VAT and
shipping costs

Interleukin-18 is a member of the interleukin-1 family of cytokines with pro-inflammatory and tumor-suppressive properties. Its ability to potently enhance the production of interferon-gamma indicates in particular the crucial function of interleukin-18 as an immunomodulatory molecule. In fact, high levels of interleukin-18 are detected in human diseases associated with immunoactivation including viral or bacterial infections and chronic inflammation. Animal models sµggest suppression of interleukin-18 bioactivity as a novel therapeutic concept specifically for the treatment of chronic inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. It is the only cytokine with a unique capacity to induce T helper 1 or T helper 2 polarization, depending on the immunologic context.

rec. Rat Interleukin-18 (rrIL-18) 1 mg - C6089.1000

rec. Rat Interleukin-18 (rrIL-18) 1 mg - C6089.1000

Productnumber: C6089.1000

Deutsch rec. Ratten Interleukin-18 (rrIL-18) 1 mg
Antikörper & Zytokine

Source: Escherichia Coli.

Technical Data: Purity: > 95.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rrIL-18 is soluble in water and most aqueous buffers below and above the isoelectric point. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rrIL-18.

Shipping/Storing-Information: shipped at RT, stored at -20°C

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