Epoxomicin 50 µg

Proteasome inhibitor

Cell permeable, potent, and selective proteasome inhibitor. More potent than Lactocystin. Inhibits the chymotrypsin-like, trypsin-like, and peptidylglutamyl peptide-hydrolyzing activities of the proteasome. Meng L. et al., Epoxomicin, a potent and selective proteasome inhibitor, exhibits in-vivo antiinflammatory activity (1999), 96, 10403; Hanada M. et al., Epoxomicin, a new antitumor agent of microbial origin., J. Antibiot. (1992), 45, 1746.