methylated Ubiquitin, min. 95% 5 mg

Methylated Ub can form an E1-catalyzed active thioester at the C-terminus allowing the molecule to be transferred to the lysines of substrate proteins (mono-ubiquitination).

Ideal for the reduction in polyUb chain length as well as conjµgation rates. Synthesised by reductive methylation of amines resulting in ubiquitin unable to form polyUb chains via lysine linkages with other Ub molecules.