Yersiniabactin (Fe-free) 1 mg

Siderophores

Siderophores (Greek for iron carrier) are a group of about 200 iron (Fe3+) binding chelating compounds (oligopeptides) produced by bacteria, fungi and plant roots, secreted to the surrounding medium. Siderophores show a very high affinity to Fe3+ ions, which allows to overcome the very low availability of soluble Fe3+ ions.

A Siderophore (Greek for iron carrier) is an iron chelating compound secreted by microorganisms. Iron Fe3+ ions have a very low solubility at neutral pH and therefore cannot be utilized by organisms. Siderophores dissolve these ions by chelation as soluble Fe3+ complexes that can be taken up by active transport mechanisms. Many siderophores are nonribosomal peptides. Examples of siderophores produced by various bacteria and fungi are ferrichrome (Ustilago sphaerogena), enterobactin (Escherichia coli), mycobactin (Mycobacterium), enterobactin and bacillibactin (Bacillus subtilis), ferrioxamine B (Streptomyces pilosus), fusarinine C (Fusarium roseum), yersiniabactin (Yersinia pestis), vibriobactin (Vibrio cholerae), azotobactin (Azotobacter vinelandii), pseudobactin (Pseudomonas B 10), erythrobactin (Saccharopolyspora erythraea) or ornibactin (Burkholderia cepacia).