Control peptide Amyloid-? (42-1) human 5 mg - P2251.0005

Package Size: 5 mg Amyloid-ß-peptides: Characteristic of Alzheimer disease is the accumulation of amyloid plaques in the brain. The major components of these plaques are 39-42 residue-long amyloid-ß-peptides, which form insoluble fibrils via self-assembly. The amyloid-ß-peptides are fragments of the broadly distributed, membrane-bound amyloid precursor protein APP, encoded on chromosome 21. They are formed from the proteolytic cleavage of APP by ß- and g-secretases. Cleavage occurs after residue 40 or after residue 42. Even slightly increased amounts of amyloid-ß1-42 are described to be sufficient to cause Alzheimer's disease.

Control peptide Amyloid-? (42-1) human Productdetails (pdf)

Source: synthetic

Technical Data: sequence: AIVVGGVMLGIIAGKNSGVDEAFFVLKQHHVEYGSDHRFEAD; purity: >95% (HPLC).

Shipping / Storing Information: shipped at RT, store at -20°C

Productnumber: P2251.0005

changedate: 1.1.2012

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