rec. Human Epidermal Growth Factor (rHuEGF)

rec. Human Epidermal Growth Factor (rHuEGF)


Artikel-Nr.: C6033.0100

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Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo... mehr
Produktinformationen "rec. Human Epidermal Growth Factor (rHuEGF)"

Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. EGF is believed to exist as a membrane bound molecule which is proteolytically cleaved to generate the 53 amino acid peptide hormone that stimulates cells to divide. EGF stimulated the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.

Recombinant Human EGF produced in E.coli is a single, non-glycosylated, polypeptide of 53 amino acids and a molecular weight of 6222 Dalton.

Amino acid sequence: NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR

Biological activity:
Genaxxon’s rHuEGF is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of BALB/c 3T3 cells (measured by 3H-thymidine uptake) is 0.1ng/mL, corresponding to a specific activity of 1x10E7 units/mg.

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Specifications: Purity: > 98.0% (by RP-HPLC, SDS-PAGE). First 5 amino acids: NSDSE... mehr
 

Technische Daten:

Specifications:
Purity: > 98.0% (by RP-HPLC, SDS-PAGE).
First 5 amino acids: NSDSE

Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rHuEGF is soluble in water and most aqueous buffers above the isoelectric point (pI=4.49)

Quelle

Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 32-16-04-90
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Hier finden Sie Informationen und weiterführende Literatur zu rec. Human Epidermal Growth Factor (rHuEGF). Für weitere Dokumente (Zertifikate mit weiteren Lotnummern, Sicherheitsdatenblätter in anderer Sprache, weitere Produktinformationen) wenden Sie sich bitte an Genaxxon biosience unter: info@genaxxon.com oder Tel.: +49 731 3608 123.