rec. Human Granulocyte Colony Stimulating Factor (rHu G-CSF)

rec. Human Granulocyte Colony Stimulating Factor (rHu G-CSF)


Artikel-Nr.: C6038.0002

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G-CSF is a cytokine that controls the production, differentiation, and function of granulocytes.... mehr
Produktinformationen "rec. Human Granulocyte Colony Stimulating Factor (rHu G-CSF)"

G-CSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for the G-CSF gene. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This csf induces granulocytes.

Rec. human Granulocyte Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain of 175 amino acids and a molecular mass of 18.8 KDa.

Biological activity: The ED50, calculated by the dose-dependant proliferation of murine NFS-60 indicator cells (measured by 3H-thymidine uptake) is <0.1ng/mL, corresponding to a Specific Activity of 100,000,000 IU/mg.

Synonyms: CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF.

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Specifications: Purity: >98% (HPLC, SDS-PAGE) GCSF was lyophilized after extensive dialysis... mehr
 

Technische Daten:

Specifications:
Purity: >98% (HPLC, SDS-PAGE)
GCSF was lyophilized after extensive dialysis against 10mM sodium acetate buffer pH=4.
First five amino acids: Met-Thr-Pro-Leu-Gly.

Quelle

Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 32-16-04-90
Dokumente - Protokolle - Downloads mehr


Dokumente - Protokolle - Downloads

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