RNAi - CRISPR/Cas9
Individual esiRNAs ideal for the functional characterization of single genes.
esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock.
esiRNAs targeting transcripts from 1,761 human and 643 mouse non-coding genomic regions.
CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA fragment with homology arms.
Cas9-Dead-NLS Protein
Das Cas9-Dead-NLS-Protein ist aufgrund der D10A- und H840A-Substitutionen katalytisch inaktiv ("dead"). Somit bindet Cas9-Dead-NLS an DNA, modifiziert es jedoch nicht. Diese...
ab 234,00 € *
Cas9-Dead-NLS-EGFP
Dieses Cas9-Protein ist aufgrund der D10A- und H840A-Substitutionen katalytisch inaktiv ("tot"). Auf das NLS folgt eine C-terminale Enhanced Green-Fluorescence Protein (EGFP)...
ab 258,00 € *
Cas9-Nickase-NLS
Cas9-Nickasen, mutierte Formen des Cas9-Proteins, spalten nur den zu der gRNA komplementären Strang und erzeugen einen Bruch in der doppelsträngigen (ds)DNA. Daher...
ab 234,00 € *
Cas9-NLS (CRISPR associated protein 9)
The Genaxxon Cas9-NLS represents the wild-type Cas9 nuclease from S. pyogenes , fused with a C-terminal NLS. Currently, the best-established Cas9 protein in the field with...
ab 234,00 € *
Cas9-NLS-EGFP
Diese innovative Cas9-Nuklease besteht aus einer Cas9-Sequenz aus Streptococcus pyogenes, gefolgt von einer Kernlokalisierungssequenz (nuclear localization sequence, NLS) und...
ab 258,00 € *
Cas9-NLS-tagRFP - Cas9 mit rot...
Als weitere innovative Cas9-Nuklease bei Genaxxon gibt nun nach NLS eine am C-terminalen Ende rot fluoreszierende Proteinsequenz (tagRFP). Die Transfektionseffizienz von...
ab 258,00 € *
CRISPRfect E Transfektionsreagenz - 35µL
Speziell auf den Einsatz in CRISPR/Cas9 Systemen zugeschnitten. Die Zusammensetzung des lipidbasierenden Transfektionsreagenz wurde speziell auf den Transfer von single guide...
144,00 € *
esiCRISPR Kit-wt
The esiCRISPR Kit applies the CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on...
550,00 € *
esiRNA - Negative Controls
Negative controls: - RLUC (Renilla Luciferase) - FLUC (Firefly Luciferase) - EGFP (enhanced green-fluorescent protein) Transfection with these esiRNAs should have...
ab 174,00 € *
esiRNA - Positive Controls
Positive controls: - human/mouse Eg5 (KIF11) - Validated esiRNAs. Many common gene targets, including LAMIN A, PLK4, and AURKB, were validated on mRNA and protein level....
ab 174,00 € *
GFP-targeting guide RNA for CRISPR
Purified gRNA, which targets sequences encoding green-fluorescent protein (GFP), or enhanced GFP. This GFP-targeting gRNA may serve as a positive control in down-stream assays,...
69,00 € *
No target guide RNA for CRISPR
Purified gRNA, which has no genomic target in human, rat and mouse. This non-targeting gRNA serves as a tool for establishing non-toxic transfection conditions, or as a...
69,00 € *
single guide RNA - custom made
The design and synthesis of guide RNA requires expertise and experience, and is time-consuming! If you need high-quality custom made guide RNA (gRNA) as a tool for your...
145,80 € *
