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Chemokines

Chemokines are a subset of cytokines. They are signaling proteins (composed of 75-125 amino acids), which are responsible for chemotaxis, that is, the movement in cells and tissues, but also in the blood. They are produced and secreted by the cells themselves. The receptive for the respective chemokine cells migrate to where the highest chemokine concentration prevails. This Chemokines play an important role in the immune response, but also in organ development.

According to their chromosomal location there are two subfamilies of Chemokines:
- CXC-Chemokines (also: Alpha-Chemokines, mainly mapped on human chromosome 4; e.g. CXCL8 or rHuIL-8 for chemotaxis of neutrophile cells), with two Cysteine residues at the N-terminal end, separated by one amino acid
- CC-Chemokines (also: Beta-Chemokines, mainly mapped on human chromosome 17; e.g.human HCC-1 or rHuHCC), with two adjacent Cysteine residues at the Amino-terminal end

   
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No image available Human HCC-1 (rHuHCC)

HCC-1 is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract Human monocytes at 5.0-20.0 ng/mL.

From €178.83 *

No image available Human MCP-2 (rHuMCP-2)

MCP-2 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-2 to chemoattract human peripheral blood at 10-100ng/mL.

From €178.83 *

No image available HuPF-4

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role...

From €170.89 *

No image available Murine MCP-3 (rMMCP-3)

Murine MCP-3 is fully biologically active when compared to standard. The specific activity as determined by the ability of Murine MCP-3 to chemoattract Balb/C mouse spleen MNCs...

From €178.83 *

No image available Rat MCP-1 (MCAF), rec.

rR-MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of Rat MCP-1 to chemoattract human peripheral blood at...

From €178.83 *

No image available rec. Human Interleukin-8 (aa 1-72) (rHuIL-8)

Synonyms: IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte...

From €164.52 *

No image available rec. Human Stromal Cell-Derived Factor-1...

SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is...

From €170.89 *

No image available Human MCP-4, rec.

MCP-4 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-4 to chemoattaract human monocytes at 10-100ng/mL.

From €178.83 *

No image available Human MIP-1alpha, rec.

UV spectroscopy at 280 nm using the absorbency value of 0.9 as the extinction coefficient for a 0.1% (1mg/mL) solution. This value is calculated by the PC GENE computer...

From €178.83 *

No image available Human MIP-1beta, rec.

rHuMIP-1 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract Human blood monocytes using a concentration of 5-20...

From €178.83 *

No image available Human MIP-4, rec.

Murine Macrophage Inflammatory Protein-4 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract Human T lymphocytes...

From €178.83 *

No image available rec. human Neutrophil Activating Protein-2...

Chemokine (C-X-C motif) ligand (CXCL7) is a small cytokine belonging to the CXC chemokine family. It is a protein that is released in large amounts from platelets following...

From €145.00 *

No image available Murine Eotaxin, rec.

The Biological activity was determined by measuring the dose dependent phosphorylation of ERK1 and ERK2 in CCR3 transfected 293 cells. Significant ERK phosphorylation is...

From €178.83 *

No image available Murine MIP-1alpha, rec.

Murine Macrophage Inflammatory Protein-1 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract of Balb3/C...

From €178.83 *

No image available Murine MIP-1beta, rec.

Murine Macrophage Inflammatory Protein-1 beta is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract Human blood...

From €178.83 *

No image available rec. Murine Stromal Cell-Derived Factor-1...

Recombinant Murine Stromal Cell-Derived Factor-1 beta (CXCL12)

From €170.89 *

No image available rec. human MIP-3beta

Chemokine (C-C motif) ligand 19 (CCL19) is a small cytokine belonging to the CC chemokine family that is also known as EBI1 ligand chemokine (ELC) and macrophage inflammatory...

From €145.00 *

No image available rHu-MCP-1 (MCAF), rec.

rHu-MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-1 to chemoattract human Monocytes using a...

From €178.83 *

No image available rHuENA-78

Recombinant Human Epithelial Neutrophil-Activating Protein 78

From €170.89 *

No image available rHuEotaxin

Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by...

From €170.89 *

No image available rHuEotaxin-His

Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by...

From €170.89 *

No image available rHuExodus-2

Recombinant Human Exodus-2 (CCL21)

From €170.89 *

No image available rHuFractalkine - human Fractalkine

The soluble form of Fractalkine is chemotactic for t-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes adhesion of those leukocytes...

From €145.00 *

No image available rHuGRO gamma (CXCL3)

GRO-gamma is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract CXCR2 transfected 293 cells using...

From €178.83 *

No image available rHuGRO-a

Recombinant Human GRO-alpha (CXCL1)

From €170.89 *

No image available rHuGRO-b

Recombinant Human GRO-beta (CXCL2)

From €170.89 *

No image available rHuGRO-g

Recombinant Human GRO-gamma (CXCL3)

From €170.89 *

No image available rHuHCC

Recombinant Human HCC-1 (CCL14)

From €170.89 *

No image available rHuI-309

Recombinant Human I-309 (CCL1)

From €170.89 *

No image available rHuI-TAC

Recombinant Human I-TAC (CXCL11)

From €170.89 *

No image available rHuI-TAC His

Recombinant Human I-TAC (CXCL11) His Tag

From €170.89 *

No image available rHuIL-8 (aa 1-77)

Synonyms: IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte...

From €170.89 *

No image available rHuIL-8 (aa 23-99) His

Synonyms: IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte...

From €170.89 *

No image available rHuIP-10

Chemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein. CXCL10 is...

From €170.89 *

   
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