rec. Human Fibroblast Growth Factor-basic (rHuFGF-b)

FGF-beta - Fibroblast Growth Factor 2


Artikel-Nr.: C6034.0010

Shipping: shipped at RT, stored at -20°C

Sofort versandfertig, Lieferzeit 1-2 Werktage

125,00 € *

Gewicht:

Wählen Sie bitte die gewünschte Packungsgröße aus.

Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF... mehr
Produktinformationen "rec. Human Fibroblast Growth Factor-basic (rHuFGF-b)"

Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

Rec. human Fibroblast Growth Factor-2 (FGF-2 / FGF-basic) produced in E.Coli is a single, non-glycosylated, polypeptide chain of 154 amino acids and a molecular mass of 17.2kDa.

Biological activity: The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5ng/mL, corresponding to a specific activity of 2,000,000 Units/mg.

Amino acid sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS.

Synonyms: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.

Weitere Artikel passend zu "rec. Human Fibroblast Growth Factor-basic (rHuFGF-b)"
Specifications: Purity: >98% (by HPLC) Lyophilized from a concentrated (1mg/mL) solution in... mehr
 

Technische Daten:

Specifications:
Purity: >98% (by HPLC)
Lyophilized from a concentrated (1mg/mL) solution in PBS, pH7.4
Biological activity:
The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5 ng/mL, corresponding to a specific activity of 2,000,000 Units/mg.

Quelle

Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads mehr

Dokumente - Protokolle - Downloads

Hier finden Sie Informationen und weiterführende Literatur zu rec. Human Fibroblast Growth Factor-basic (rHuFGF-b). Für weitere Dokumente (Zertifikate mit weiteren Lotnummern, Sicherheitsdatenblätter in anderer Sprache, weitere Produktinformationen) wenden Sie sich bitte an Genaxxon biosience unter: info@genaxxon.com oder Tel.: +49 731 3608 123.

 
 
 
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "rec. Human Fibroblast Growth Factor-basic (rHuFGF-b)"
Bewertung schreiben
Bewertungen werden nach Überprüfung freigeschaltet.
Bitte geben Sie die Zeichenfolge in das nachfolgende Textfeld ein.

Die mit einem * markierten Felder sind Pflichtfelder.