rec. Human Keratinocyte Growth Factor (rHuKGF)

rec. Human Keratinocyte Growth Factor (rHuKGF)


Artikel-Nr.: C6035.0002

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Recombinant Human KGF produced in E.Coli is a single, non-glycosylated, polypeptide chain... mehr
Produktinformationen "rec. Human Keratinocyte Growth Factor (rHuKGF)"

Recombinant Human KGF produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 164 amino acids and having a molecular mass of 18,995 Dalton. The ED50, calculated by the dose-dependant stimulation of KGF-responsive BaF3 indicator cells (measured by 3H-thymidine uptake) is 2.0ng/mL (Limit of acceptance: 5.0 ng/mL), corresponding to a specific activity of 10(5) Units/mg. Genaxxon’s rHuKGF biological activity was measured by the KGF’s mitogenic activity on BaF3 cells expressing the KGF receptor. KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

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Purity: > 99.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile... mehr
 

Technische Daten:

Purity: > 99.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rHuKGF is soluble in water and most aqueous buffers above the isoelectric point (pI=10.42).

Quelle

Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
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Dokumente - Protokolle - Downloads

Hier finden Sie Informationen und weiterführende Literatur zu rec. Human Keratinocyte Growth Factor (rHuKGF). Für weitere Dokumente (Zertifikate mit weiteren Lotnummern, Sicherheitsdatenblätter in anderer Sprache, weitere Produktinformationen) wenden Sie sich bitte an Genaxxon biosience unter: info@genaxxon.com oder Tel.: +49 731 3608 123.

 
 
 
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