Amyloid-beta (1-40). human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

Amyloid-beta (1-40). human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV


Artikel-Nr.: P2249.0001

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[beta]-Amyloid (1-40), human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV belongs to the... mehr
Produktinformationen "Amyloid-beta (1-40). human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV"

[beta]-Amyloid (1-40), human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV belongs to the Amyloid-ß-peptides.

The characteristic of Alzheimer disease is the accumulation of amyloid plaques in the brain. The major components of these plaques are 39-42 residue-long amyloid-ß-peptides, which form insoluble fibrils via self-assembly. The amyloid-ß-peptides are fragments of the broadly distributed, membrane-bound amyloid precursor protein APP, encoded on chromosome 21. They are formed from the proteolytic cleavage of APP by ß- and g-secretases. Cleavage occurs after residue 40 or after residue 42. Even slightly increased amounts of amyloid-ß1-42 are described to be sufficient to cause Alzheimer's disease.

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Weitere Artikel passend zu "Amyloid-beta (1-40). human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV"
Specifications: Purity: >95% (HPLC) Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV mehr
 

Technische Daten:

Specifications:
Purity: >95% (HPLC)
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

Applikation:

Fibrilization, fibrillogenesis studies

Quelle

synthetic

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads mehr

Dokumente - Protokolle - Downloads

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