FSL-1 TLR2/TLR6 Agonist



Artikel-Nr.: P2212.0001

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FSL-1 (Pam2C-GDPKHPKSF) showed higher activity than MALP-2 when tested for its capability to... mehr
Produktinformationen "FSL-1 TLR2/TLR6 Agonist"

FSL-1 (Pam2C-GDPKHPKSF) showed higher activity than MALP-2 when tested for its capability to activate THP-1 cells to produce TNF-alpha and on HEK293 cells transfected with TLR2 and TLR6 to produce NF-kappaB (Okusawa et al. 2004). It was shown that the activity of FSL-1 is TLR2 and TLR6 dependent. A single amino acid substitution from F to R (FSL-2, Pam2C-GDPKHPKSR, Cat-No- P2219) reduced the activity significantly (Okusawa et al. 2004). FSL-1 (P2212) is more favourable than MALP-2 with respect to solubility in aqueous solutions. FSL-1 is provided as stereochemically defined compounds and as mixture of stereoisomers. Lipopeptides with the S-dihydroxypropyl moiety are not active and therefore suitable as negative controls. Additionally, analogues with different labels or tags are available. Genaxxon offers further analogues differing in the peptide moiety for improved physico-chemical features and high reproducible biological activity. Please inquire for other peptides or more information: info@genaxxon.com.

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Specifications: As lipopeptides are very hydrophobic it is most often not possible to purify... mehr
 

Technische Daten:

Specifications:
As lipopeptides are very hydrophobic it is most often not possible to purify them by HPLC. For that reason it is not possible to give purity values (in %) for our standard lipopeptides.
Mixture of R,R and R,S stereoisomers
Sequence: Pam2CGDPKHPKSF

Quelle

synthetic

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
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Hier finden Sie Informationen und weiterführende Literatur zu FSL-1 TLR2/TLR6 Agonist. Für weitere Dokumente (Zertifikate mit weiteren Lotnummern, Sicherheitsdatenblätter in anderer Sprache, weitere Produktinformationen) wenden Sie sich bitte an Genaxxon biosience unter: info@genaxxon.com oder Tel.: +49 731 3608 123.