[beta]-Amyloid (10-20) - YEVHHQKLVFF

[beta]-Amyloid (10-20) - YEVHHQKLVFF


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[beta]-Amyloid (10-20) (peptide sequence: YEVHHQKLVFF) ist used as a test peptide for the... mehr
Produktinformationen "[beta]-Amyloid (10-20) - YEVHHQKLVFF"

[beta]-Amyloid (10-20) (peptide sequence: YEVHHQKLVFF) ist used as a test peptide for the hydrophilic part of the complete Amyloid beta 1-42 peptide.

Amyloid-beta (1-42) human is an Alzheimer desease peptide. Characteristic of Alzheimer disease is the accumulation of amyloid plaques in the brain. The major components of these plaques are 39-42 residue-long amyloid-ß-peptides, which form insoluble fibrils via self-assembly. The amyloid-ß-peptides are fragments of the broadly distributed, membrane-bound amyloid precursor protein APP, encoded on chromosome 21. They are formed from the proteolytic cleavage of APP by ß- and g-secretases. Cleavage occurs after residue 40 or after residue 42. Even slightly increased amounts of Amyloid-beta 1-42 are described to be sufficient to cause Alzheimer's disease.

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Weitere Artikel passend zu "[beta]-Amyloid (10-20) - YEVHHQKLVFF"
Specifications: Sequence: YEVHHQKLVFF Purity: >95% (HPLC) mehr
 

Technische Daten:

Specifications:
Sequence: YEVHHQKLVFF
Purity: >95% (HPLC)

Applikation:

Fibrilization, fibrillogenesis studies

Quelle

synthetic

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads mehr


Dokumente - Protokolle - Downloads

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