RNAi - CRISPR/Cas9

Individual esiRNAs ideal for the functional characterization of single genes.
esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock.
esiRNAs targeting transcripts from 1,761 human and 643 mouse non-coding genomic regions.

CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA fragment with homology arms.

Individual esiRNAs ideal for the functional characterization of single genes. esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock. esiRNAs targeting... mehr erfahren »
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RNAi - CRISPR/Cas9

Individual esiRNAs ideal for the functional characterization of single genes.
esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock.
esiRNAs targeting transcripts from 1,761 human and 643 mouse non-coding genomic regions.

CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA fragment with homology arms.

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Cas9-Dead-NLS Protein
Cas9-Dead-NLS Protein
Das Cas9-Dead-NLS-Protein ist aufgrund der D10A- und H840A-Substitutionen katalytisch inaktiv ("dead"). Somit bindet Cas9-Dead-NLS an DNA, modifiziert es jedoch nicht. Diese Eigenschaft ermöglicht ein spezifisches genomisches Targeting,...
ab 234,00 € *
Cas9-Dead-NLS-EGFP
Cas9-Dead-NLS-EGFP
Dieses Cas9-Protein ist aufgrund der D10A- und H840A-Substitutionen katalytisch inaktiv ("tot"). Auf das NLS folgt eine C-terminale Enhanced Green-Fluorescence Protein (EGFP) -Sequenz. Der EGFP-Tag bietet viele Anwendungsmöglichkeiten,...
ab 258,00 € *
Cas9-Nickase-NLS
Cas9-Nickase-NLS
Cas9-Nickasen, mutierte Formen des Cas9-Proteins, spalten nur den zu der gRNA komplementären Strang und erzeugen einen Bruch in der doppelsträngigen (ds)DNA. Daher müssen Cas9-Nickasen mit zwei verschiedenen gRNAs zusammengesetzt werden,...
ab 234,00 € *
Cas9-NLS (CRISPR associated protein 9)
Cas9-NLS (CRISPR associated protein 9)
The Genaxxon Cas9-NLS represents the wild-type Cas9 nuclease from S. pyogenes , fused with a C-terminal NLS. Currently, the best-established Cas9 protein in the field with most publications. Cas9-NLS (CRISPR associated protein 9) is an...
ab 234,00 € *
Cas9-NLS-EGFP
Cas9-NLS-EGFP
Diese innovative Cas9-Nuklease besteht aus einer Cas9-Sequenz aus Streptococcus pyogenes, gefolgt von einer Kernlokalisierungssequenz (nuclear localization sequence, NLS) und einem C-terminalen Enhanced Green Fluorescent Protein (EGFP)...
ab 258,00 € *
Cas9-NLS-tagRFP - Cas9 protein with red fluorescent tag
Cas9-NLS-tagRFP - Cas9 mit rot fluoreszierendem...
Cas9-NLS-taqRFP hat, als weitere innovative Cas9-Nuklease, nach NLS eine am C-terminalen Ende rot fluoreszierende Proteinsequenz (tagRFP). Die Transfektionseffizienz von Cas9-NLS-tagRFP ist so hoch wie bei der unmarkierten...
ab 258,00 € *
CRISPRfect E Transfektionsreagenz - 35µL
CRISPRfect E Transfektionsreagenz - 35µL
Speziell auf den Einsatz in CRISPR/Cas9 Systemen zugeschnitten. Die Zusammensetzung des lipidbasierenden Transfektionsreagenz wurde speziell auf den Transfer von single guide (g)RNA beladenen Cas9 Proteinen in die meisten adhärenten...
144,00 € *
esiCRISPR Kit-wt
esiCRISPR Kit-wt
The esiCRISPR Kit applies the CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA...
550,00 € *
esiRNA - Negative Controls
esiRNA - Negative Controls
esiRNA negative controls: - RLUC (Renilla Luciferase) - FLUC (Firefly Luciferase) - EGFP (enhanced green-fluorescent protein) Transfection with these esiRNAs should have no effect, if the corresponding target is not expressed by the...
ab 174,00 € *
esiRNA - Positive Controls
esiRNA - Positive Controls
Positive controls: - human/mouse Eg5 (KIF11) - Validated esiRNAs. Many common gene targets, including LAMIN A, PLK4, and AURKB, were validated on mRNA and protein level. Transfection with this esiRNA is ideal to optimize the most...
ab 174,00 € *
GFP-targeting guide RNA for CRISPR
GFP-targeting guide RNA for CRISPR
GFP-targeting guide RNA for CRISPR is purified gRNA, which targets sequences encoding green-fluorescent protein (GFP), or enhanced GFP. This GFP-targeting gRNA may serve as a positive control in down-stream assays, monitoring the success...
79,00 € *
No target guide RNA for CRISPR
No target guide RNA for CRISPR
No target guide RNA for CRISPR is purified gRNA, which has no genomic target in human, rat and mouse. This non-targeting gRNA serves as a tool for establishing non-toxic transfection conditions, or as a negative control in down-stream...
69,00 € *
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