Artocarpus integrifolia lectin (Jacalin)
Order number: D1501.0010
Shipping: shipped on wet ice, store at -20°C Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.
Prices plus VAT plus shipping costs
Artocarpus integrifolia lectin (Jacalin) is isolated from jackfruit seeds and purified by affinity chromatography. The lectin belongs to the family of galactose-binding lectins and has a tetrameric two-chain structure with a weight of 66 kDa. Lectins are, due to their specific binding to carbohydrate structures on the cell surface or elsewhere useful in haematology, immunology or as specific markers for membrane glycoprotein structures. Jacalin is preferably used in applications to isolate IgA from human serum, isolating human plasma glycoproteins and for applications in histochemistry. The lectin is blood group non-specific after neuraminidase treatment and agglutinates human erythrocytes at a concentration of >7,8µg/mL. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the a-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure.
Technical Data:
Specifications:
Assay: >80% based on OD280nm
Identity: one band in SDS-PAGE
Agglutination activity: Agglutinates human erythrocytes of blood group 0 at a concentration of <10 µg/mL
Source
Jack FruitSicherheits Hinweise / Safety
Klassifizierungen / Classification
eclass-Nr: 32-16-04-05Dokumente - Protokolle - Downloads
Here you will find information and further literature on Artocarpus integrifolia lectin (Jacalin). For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.