Kanamycin sulfate 50 mg/mL
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Product information "Kanamycin sulfate 50 mg/mL"
Kanamycin is very stable as a solution in the pH range 6-8 and can be stored for 6-8 months at room temperature (with only 1-2% loss of activity). Autoclaving at 120°C (even for more than 1 hour) leads to only a slight loss of activity (5%). When exposed to air, Kanamycin may change colour but without losing much of its activity. The change in colour can be prevented by antioxidants.
Aminoglycoside-antibiotic with broad antibacterial spectrum, (including mycobacteria, many gram-positive and most gram-negative organisms), Additive in culture media for the isolation of group D Streptococci on Kanamycin Esculin Azide Agar (Mossel et al.) or for selection of transformed plant cells containing the neomycin phosphotransferase (for kanamycin resistance), on a kanamycin-medium. Inhibits formation of peptide bonds, Cox d. et al. (1977) Sammes, P.G (ed.) Topics in antibiotics chemistry Vol. I, Chichester, Horwood, pp. 1-190, Lancini G., Parenti F. (1982) Antibiotics: Springer, New York, Pestka S. (1971) Annu. Rev. Microbiol. 25, 487-562.
Specifications:
Sterile filtered solution of 50 mg/mL
C18H36N4O11xH2SO4xH2O
MW = 600.6 g/mol
Sicherheits Hinweise / Safety
Klassifizierungen / Classification
Documents:
Safety Data SheetCertificate
Category List
Source: NCBI PubMed
Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663
Orwah Saleh, Katrin Flinspach, Lucia Westrich, Andreas Kulik, Bertolt Gust, Hans-Peter Fiedler, Lutz Heide
Beilstein J Org Chem. 2012; 8: 501–513.
doi: 10.3762/bjoc.8.57
PMCID: PMC3326630
The biosynthetic genes for prenylated phenazines are located at two different chromosomal loci of Streptomyces cinnamonensis DSM 1042
Kerstin Seeger, Katrin Flinspach, Elisa Haug‐Schifferdecker, Andreas Kulik, Bertolt Gust, Hans‐Peter Fiedler, Lutz Heide
Microb Biotechnol. 2011 Mar; 4(2): 252–262.
doi: 10.1111/j.1751-7915.2010.00234.x
PMCID: PMC3818865
Aromatic Prenylation in Phenazine Biosynthesis: DIHYDROPHENAZINE-1-CARBOXYLATE DIMETHYLALLYLTRANSFERASE FROM STREPTOMYCES ANULATUS
Orwah Saleh, Bertolt Gust, Björn Boll, Hans-Peter Fiedler, Lutz Heide
J Biol Chem. 2009 May 22; 284(21): 14439–14447.
doi: 10.1074/jbc.M901312200
PMCID: PMC2682892
