HighPure Propidium iodide
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Product information "HighPure Propidium iodide"
HighPure Propidium iodide (3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide) for selective labeling of DNA in dead cells as cell membrane integrity excludes propidium iodide from staining viable and apoptotic cells. Propidium iodide may be used in tumor diagnosis flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are in early apoptosis process. Can also be used for the study of micronuclear morphology of protozoa.
Propidium iodide can be excited by light with wavelenghts in the visible range and bleaches slowly, having clear advantages over DAPI.
CAUTION: Potent carcerogenic agent. Valet G. et al. (1987) Blut 49, 37-43. Fluorescent stain for nucleic acids. At a concentration of 1 µg/mL, probably all DNA binding sites are saturated.
Specifications:
Assay (HPLC): min. 95%
Absorption maximum: 530 - 540nm
Formula: C27H34I2N4
MW = 668.4 g/mol
Applikation / Application:
For apoptosis research. Propidium iodide (PI) is a popular red-fluorescent nuclear and chromosome counterstain. Since propidium iodide is not permeant to live cells, it is also commonly used to detect dead cells in a population.Sicherheits Hinweise / Safety
Klassifizierungen / Classification
Documents:
Safety Data SheetCertificate
Category List
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