NGS DNA Purification MagBeads

NGS DNA Puri MagBeads is a SPRI-based chemistry that speeds and simplifies nucleic acid size selection and PCR purification for DNA and/or RNA library preparation for Next Generation sequencing. It is compatible with mainstream NGS library prepared kits.

NGS DNA Puri MagBeads utilize SPRI (Solid Phase Reverse Immobilization) paramagnetic bead technology to enable DNA purification and size selection during NGS library construction.
NGS DNA Puri MagBeads are compatible with most NGS library construction kits (DNA, RNA). The kit allows users to seamlessly replace competitor beads (i.e. AMPure XP Beads) in current bead clean-up and size selection protocols without loss of efficiency.

Why Purification and Quality Control of DNA preps for NGS?
The purification step is usually necessary to remove unwanted material that might interfere with sequencing. Some NGS platforms may have tight size requirements, and discarding fragments that are too large or too small can improve sequencing efficiency by far. The optimal library size is given by the sequencing application. It is common to clean up nucleic acids using magnetic beads. Quality control is the last process before sequencing. As Subsequent experiments are time-consuming and expensive, strict quality control steps are required to ensure all samples are appropriate for their applications. Confirming the quality and quantity of DNA increases the reliability of sequencing data!

The Genaxxon NGS MagBead DNA purification kit protocol can be adapted to your current liquid handling workstation (e.g., Beckman, Hamilton, Tecan, Caliper, Perkin Elmer, Agilent and Eppendorf) utilizing your current protocol as well as it can be performed manually.