rec. human FGF-8
Order number: C4303.0005
Shipping: shipped at RT, stored at -20°C Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.
*Prices plus VAT plus shipping costs
Recombinant human FGF-8 produced in E.Coli is a single, non-glycosylated, polypeptide of 194 amino acids and a MW of 22.5 kDa. GF8 is part of the fibroblast growth factor family. FGF family members have wide mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF8 supports androgen and anchorage independent growth of mammary tumor cells. FGF8 over expression increases tumor growth and angiogensis. The adult expression of FGF-8 gene is restricted to testes and ovaries. FGF8 functions as an embryonic epithelial factor. FGF8 takes part in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination.
Synonyms: FGF8B, FGF-8B, FGF8-B, KAL6, HBGF-8, HBGF8, AIGF, HBGF-8, MGC149376, fibroblast growth factor 8.
Amino acid sequence: MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
Technical Data:
Specifications:
Purity: >97% (by RP-HPLC, SDS-PAGE)
Sterile Filtered White lyophilized (freeze-dried) powder.
ED50 range = 10-50ng/mL, determined by the dose dependent proliferation of mouse BALB/3T3 cells.
Optimal concentration for individual application should be determined by a dose response assay.
Source
Escherichia Coli.Sicherheits Hinweise / Safety
Klassifizierungen / Classification
eclass-Nr: 32-16-08-90Dokumente - Protokolle - Downloads
Here you will find information and further literature on rec. human FGF-8. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.