rec. Rat Interleukin-15 (rrIL15)

rec. Rat Interleukin-15 (rrIL15)


Order number: C6078.0002

Shipping: shipped at RT, stored at -20°C

Ready to ship today,
Delivery time 1-3 workdays

€170.89 *

Weight:

Please select the favoured pack size.

The protein encoded by this gene is a cytokine that regulates T and natural killer cell... more
Product information "rec. Rat Interleukin-15 (rrIL15)"

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. Rec. Interleukin-15 Rat produced in E.Coli is a single, non-glycosylated polypeptide chain of 115 amino acids and a molecular mass of 13533 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <10ng/mL, corresponding to a Specific Activity of 100,000IU/mg.

More products around "rec. Rat Interleukin-15 (rrIL15)"
Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile... more
 

Technical Data:

Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rrIL-15.

Source

Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on rec. Rat Interleukin-15 (rrIL15). For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.

 
 
 
Read, write and discuss reviews... more
Customer evaluation for "rec. Rat Interleukin-15 (rrIL15)"
Write an evaluation
Evaluations will be activated after verification.
Please enter these characters in the following text field.

The fields marked with * are required.