Order number: C6040.0006Shipping: shipped at RT, stored at -20°C
Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.
Recombinant murine GM-CSF produced in E.Coli is a single, non-glycosylated, polypeptide chain of 125 amino acids and a molecular mass of 14,285 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of murine FDC-P1 cell line is <0.2ng/mL, corresponding to a Specific Activity of 5,000,000 IU/mg. GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Synonyms: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim.
Purity: > 98.0% (by RP-HPLC, IEX-HPLC, SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. The lyophilized rmGM-CSF is soluble in water and most aqueous buffers above the isoelectric point (pI=5.9).
Sicherheits Hinweise / Safety
Klassifizierungen / Classificationeclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads
Here you will find information and further literature on rec. Murine Granulocyte Macrophage Colony Stimulating Factor (rmGM-CSF). For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: firstname.lastname@example.org or phone: +49 731 3608 123.