rec. Rat Interleukin 4 - rrIL-4
Order number: C6233.0002
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Recombinant Rat Interleukin-4 (rrIL4) is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.
Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Technical Data:
Specifications:
Purity: >95% (HPLC)
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Sicherheits Hinweise / Safety
Klassifizierungen / Classification
eclass-Nr: 34-16-04-90Dokumente - Protokolle - Downloads
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