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IL-12 is a heterodimeric cytokine that stimulates the production of interferon gamma from T-cells and natural killer cells, and also induces differentiation of Th1 helper cells. IL-12 is an initiator of cell-mediated immunity. Recombinant human Interleukin-12 produced in HEK cells is a glycosylated heterodimer, having a total molecular weight of 57kDa. The specific activity was determined by the dose-dependent release of IFN-gamma from the human NK92 cell line in presence of 20ng/mL rIL-2, and is typically 0.1-0.5ng/mL.
Purity: >95.0% (SDS-PAGE)
Sterile filtered white lyophilized (freeze-dried) powder.
This IL12 was lyophilized from 1mg/mL in 1xPBS. Heterodimer linked via a disulfide bridge between Cys.
Sicherheits Hinweise / Safety
Klassifizierungen / Classificationeclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads
Here you will find information and further literature on rec. human Interleukin 12 - rHuIL-12. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: email@example.com or phone: +49 731 3608 123.