rHuTPO

rHuTPO


Order number: C6381.0002

Shipping: shipped at RT, stored at -20°C

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

€145.00 *

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Recombinant human Thrombopoietin (rHuTPO) expressed and isoltated from HEK cells is a single,... more
Product information "rHuTPO"

Recombinant human Thrombopoietin (rHuTPO) expressed and isoltated from HEK cells is a single, non-glycosylated polypeptide of 332 amino acids and a molecular mass of 78-84 kDa depending on the glycosylation. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney hat regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets. Part of the protein (N-terminal domain) is very similar to erythropoietin, the hormone necessary for the production of erythrocytes (red blood cells).

Biological Activity:
The activity was determined by the dose-dependent stimulation of the proliferation of MO7e cells, the ED50 is 1.15ng/mL.

Amino acid sequence:

SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNELPNRTSG LETNFTASA RTTGSGLLKW QQGFRAKIPG LLNQTSRSLD QIPGYLNRIH ELLNGTRGLF PGPSRRTLGA PDISSGTSDT GSLPPNLQPG YSPSPTHPPT GQYTLFPLPP TLPTPVVQLH PLLPDPSAPT PTPTSPLLNT SYTHSQNLSQ EG

Synonyms:
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.

More products around "rHuTPO"
Specifications: Purity: >95% (determined by SDS-PAGE). Sterile filtered (0.2µm) and... more
 

Technical Data:

Specifications:
Purity: >95% (determined by SDS-PAGE).
Sterile filtered (0.2µm) and lyophilized from 0.74mg/mL in 1xPBS.

Biological Activity:
The activity was determined by the dose-dependent stimulation of the proliferation of MO7e cells, the ED50 is 1.15ng/mL.

Source

HEK cells

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on rHuTPO. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.