rec. human Fibronectin

rec. human Fibronectin

Order number: C6004.0020

Shipping: shipped at RT, stored at -20°C

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

€165.00 *


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Fibronectin takes part in several cellular processes, including tissue repair, embryogenesis,... more
Product information "rec. human Fibronectin"

Fibronectin takes part in several cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion.Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males, and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin consists in 2 main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the etracellular matrix and 2) as a soluble disulphide linked dimer found in the plasma. The plasma form is produced by hepatocytes, and the ECM form is synthesized by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin alos takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces.

Fibronectin Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 574 amino acids and having a molecular mass of 62.6kDa.

Biological activity:

Was measured by its ability to support cell attachment and spreading when used as a substratum for cell culture. The recommended concentration in this application for this effect is typically 1-5μg/cm2. Fibronectin can also be added to the media to support cell spreading at a concentration of 0.5-50μg/mL. Optimal concentrations will need to be determined for individual user applications.

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Specifications: Purity: >95% (by SEC, SDS-PAGE). Sterile filtered white lyophilized... more

Technical Data:

Purity: >95% (by SEC, SDS-PAGE).

Sterile filtered white lyophilized (freeze-dried) powder. The lyophilized rHuPGH is soluble in water and most aqueous buffers above the isoelectric point (pI=7.8).


Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 32-16-04-90
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on rec. human Fibronectin. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: or phone: +49 731 3608 123.