rec. Human Interleukin-4 (rHuIL-4)

rec. Human Interleukin-4 (rHuIL-4)

Order number: C6024.0005

Shipping: shipped at RT, stored at -20°C

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

€132.61 *


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Recombinant human IL-4 from  E.Coli is a single, non-glycosylated polypeptide of 130 amino... more
Product information "rec. Human Interleukin-4 (rHuIL-4)"

Recombinant human IL-4 from E.Coli is a single, non-glycosylated polypeptide of 130 amino acids and a molecular mass of 15 kDa.

IL-4 is a pleiotropic cytokine produced by activated T cells. IL-4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL-13, which may contribute to many overlapping functions of IL-4 and IL-13.

STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. IL-4, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-4 gene particularly close to IL-13. IL-4, IL1-3 and IL-5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Synonyms: BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.


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Specifications: Purity: min. 97% (HPLC).  IL-4 was lyophilized from a 0.2µm filtered... more

Technical Data:

Purity: min. 97% (HPLC). 
IL-4 was lyophilized from a 0.2µm filtered concentrated (1mg/mL) solution in PBS, pH 7.4.

Biological Activity:
The ED50 as determined by the dose-dependent stimulation of TF-1 cells is <0.2ng/mL, corresponding to a Specific Activity of 5,000,000 IU/mg.


For in vitro applications. A dose-response assay should be performed to determine the optimal concentration for specific experiments.


Escherichia Coli.

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 32-16-04-90
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on rec. Human Interleukin-4 (rHuIL-4). For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: or phone: +49 731 3608 123.