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rec. human FGF-8

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  • Fast service
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€253.50*

Weight
Product number: C4303.0025
Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

Shipment: not cooled. Stored at -20°C. For laboratory usage only!
Product information "rec. human FGF-8"

Recombinant human FGF-8 produced in E.Coli is a single, non-glycosylated, polypeptide of 194 amino acids and a MW of 22.5 kDa. GF8 is part of the fibroblast growth factor family. FGF family members have wide mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF8 supports androgen and anchorage independent growth of mammary tumor cells. FGF8 over expression increases tumor growth and angiogensis. The adult expression of FGF-8 gene is restricted to testes and ovaries. FGF8 functions as an embryonic epithelial factor. FGF8 takes part in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination.

Synonyms: FGF8B, FGF-8B, FGF8-B, KAL6, HBGF-8, HBGF8, AIGF, HBGF-8, MGC149376, fibroblast growth factor 8.

Amino acid sequence: MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR

Specifications:
Purity: >97% (by RP-HPLC, SDS-PAGE)
Sterile Filtered White lyophilized (freeze-dried) powder.
ED50 range = 10-50ng/mL, determined by the dose dependent proliferation of mouse BALB/3T3 cells.
Optimal concentration for individual application should be determined by a dose response assay.


Applikation / Application:
Einheiten / Units:
Quelle / Source:
Escherichia Coli.


Sicherheits Hinweise / Safety


Klassifizierungen / Classification

eclass-Nr: 32-16-08-90
Documents - Protocols - Downloads :
Here you will find information and further literature. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.


Documents:

Product description
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Listed below are articles and references, in which the authors trust in the high quality of this Genaxxon product.
Source: NCBI PubMed