Sodium dodecyl sulfate (10%) - 5 bags

Sodium dodecyl sulfate (SDS) is an anionic detergent that denatures secondary and non-disulfide-linked tertiary protein structures. It applies a negative charge to each protein in proportion to its mass. SDS binds in a ratio of approximately 1.4g SDS per 1.0g protein, unfolding it to give a near-uniform negative charge along the length of the polypeptide chain. As a result, the distance of migration through the gel in SDS-PAGE electrophoresis can be assumed to be directly related only to the size of the protein. These SDS tablets are pre-weighed tablets. One tablet weighs 0.5g and can be dissolved in deionized water to the desired volume and concentration. SDS is also available as powder mix in pouches resulting in 1000mL of 10% or 20% sodium dodecyl sulfate solution.