Order number: M3111.0005Shipping: shipped at RT, store at +2°C to +8°C
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Bacitracin from Bacillus licheniformis consists of several peptides (A, B, C, D, E, F1-3), bacitracin A, a cyclic dodecapeptide, being the most important component with approximately 70%. For its bactericidal action, the presence of divalent cations (eg, zinc) is required, with which Bacitracin forms stable complexes. Like Vancomycin, it inhibits the biosynthesis of the cell wall (especially gram-positive bacteria and cocci) by binding to bactoprenylpyrophosphate.
Bacitracin is very stable as a dry substance (moisture content <1%) with a shelf life of about 15 months at room temperature and is stable for about 15 months. At higher temperatures (>55°C) the antibiotic is unstable.
Bacitracin is readily soluble in water or alcohols (1g/mL) and forms stable salts with zinc. In aqueous solutions, it is relatively stable in the acidic pH range (pH4-5) and relatively rapidly inactivated in the range above pH5 (pH5 - 9) at 25°C. Above pH8 it is not durable at all. In solution, 10% of the activity is lost at +2°C to +8°C within about 2 months.
Activity: min. 55 IU/mg
Solubility (1%, H2O): clear, yellow
Loss on drying: max. 5%
MP: ca. 222°C
Main component Bacitracin A.
Bacteriocidal activity requires divalent cations like Zn++.
Sicherheits Hinweise / Safety
Klassifizierungen / ClassificationEC-Nr: 215-786-2
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Here you will find information and further literature on Bacitracin powder, min. 55 IU/mg. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: email@example.com or phone: +49 731 3608 123.
Hier finden Sie Artikel und Literaturzitate, in denen die Autoren auf die hohe Qualität dieses Genaxxonprodukts vertrauen.
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Soren Hayrabedyan, Krassimira Todorova, Asma Jabeen, Gergana Metodieva, Stavri Toshkov, Metodi V. Metodiev, Milcho Mincheff, Nelson Fernández
Sci Rep. 2016; 6: 18896. Published online 2016 Jan 8. doi: 10.1038/srep18896