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Colchicine is an antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Colchicine is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as "meadow saffron"). It is suspected to cause genetic defects!
Assay: min. 95% (HPLC)
Appearance: white to yellow
Solubility: ethanol (50mg/mL), clear, yellow to yellow-green solution
MP: 150°C - 160°C (dec., lit.)
UN1544; class/PG: 6.1/I
Sicherheits Hinweise / SafetyH-Sätze: H300, H340
GHS-Symbole: GHS06, GHS08
Klassifizierungen / ClassificationEC-Nr: 200-598-5
Dokumente - Protokolle - Downloads
Here you will find information and further literature on Colchicine. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: firstname.lastname@example.org or phone: +49 731 3608 123.