3,3'-Dipropylthiacarbocyanine iodide / DiSC3(3)

Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) or DiSC3(5) can inhibit respiration and may therefore be relatively cytotoxic. 3,3'-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method. Selected applications are: Calcium channels and other ion transport systems, mitochondrial activity, neurons and brain tissue, membrane potential in intact yeast cells.

Potential-sensitive fluorescent dye used in fluorescence microscopy or fluorimetric measurements. DiSC3(5) is a well established reporter of membrane potential in bacteria.