rhCG - Corticotropin releasing hormone binding protein

rhCG - Corticotropin releasing hormone binding protein


Order number: C6461.0010

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CRH is a powerful stimulator of synthesis and secretion of preopiomelanocortin-derived peptides.... more
Product information "rhCG - Corticotropin releasing hormone binding protein"

CRH is a powerful stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. CRH concentration in the human peripheral circulation is usually low. The concentration rises during pregnancy and fall back quickly after parturition. Maternal plasma CRH most likely originates from the placenta. Human plasma has a CRH-binding protein that inactivates CRH and can inhibit inappropriate pituitary-adrenal stimulation in pregnancy.

Human recombinant CRHBP is a 34.58 kDa protein containing 308 aa and fused to a 10 aa N-Terminal His-tag.

Synonyms: Corticotropin releasing hormone binding protein, CRF-BP, CRH-BP, CRF-binding protein.

Amino acid sequence: MKHHHHHHAS YLELREAADY DPFLLFSANL KRELAGEQPY RRALRCLDML SLQGQFTFTA DRPQLHCAAF FISEPEEFIT IHYDQVSIDC QGGDFLKVFD GWILKGEKFP SSQDHPLPSA ERYIDFCESG LSRRSIRSSQ NVAMIFFRVH EPGNGFTLTI KTDPNLFPCN VISQTPNGKF TLVVPHQHRN CSFSIIYPVV IKISDLTLGH VNGLQLKKSS AGCEGIGDFV ELLGGTGLDP SKMTPLADLC YPFHGPAQMK VGCDNTVVRM VSSGKHVNRV TFEYRQLEPY ELENPNGNSI GEFCLSGL YLELREAADY DPFLLFSANL KRELAGEQPY RRALRCLDML SLQGQFTFTA DRPQLHCAAF FISEPEEFIT IHYDQVSIDC QGGDFLKVFD GWILKGEKFP SSQDHPLPSA ERYIDFCESG LSRRSIRSSQ NVAMIFFRVH EPGNGFTLTI KTDPNLFPCN VISQTPNGKF TLVVPHQHRN CSFSIIYPVV IKISDLTLGH VNGLQLKKSS AGCEGIGDFV ELLGGTGLDP SKMTPLADLC YPFHGPAQMK VGCDNTVVRM VSSGKHVNRV TFEYRQLEPY ELENPNGNSI GEFCLSGL

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Specifications: Appearance: Filtered white lyophilized powder. CRHBP Human was filtered... more
 

Technical Data:

Specifications:
Appearance: Filtered white lyophilized powder. CRHBP Human was filtered (0.4µm) and lyophilized from a 0.5mg/mL solution with 20mM TRIS and 20mM NaCl, pH7.5.

 

application:

ELISA Western blotting

Source

E.Coli

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 32-16-04-90
Dokumente - Protokolle - Downloads more


Dokumente - Protokolle - Downloads

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