Absolute Lectins

Absolute Lectins, perfect for Glycoscience!

Genaxxon is a supplier of a wide range of exceptionally pure lectins purified by affinity chromatography.

Examples of Lectins that are offered by Genaxxon bioscience are: Arachis hypogaea lectin (PNA) - Artocarpus integrifolia lectin (Jacalin) - Concanavalin A - Crotalaria juncea lectin - Galanthus nivalis lectin - Lens culinaris lectin - Narcissus pseudonarcissus lectin - Phaseolus vulgaris lectin E - Phaseolus vulgaris lectin L - Phaseolus vulgaris lectin P - Pisum sativum lectin - Triticum vulgaris lectin - Vicia ervilia lectin.

Lectins are proteins / glycoproteins of non-immunoglobulin origin that bind specifically and reversibly to carbohydrate moieties without altering the covalent structure of the glycosyl ligands.

The term ‘lectin’ is derived from the latin word legere, meaning ‘to select’. The specificity of a lectin is usually defined by the monosaccharides or oligosaccharides that are best at inhibiting the agglutination or precipitation caused by the lectin. Lectins are usually of plant origin but do occur in many types of organism; some are glycoproteins and may be soluble or membrane-bound.

The biological function of lectins is far from fully explored. Their specificity enables binding to glycoproteins and polysaccharides as well as agglutination of erythrocytes and stimulation of blood lymphocytes. Because of their ability to distinguish glycosyl ligands on human red blood cells, lectins can be used for blood typing. Immobilized lectins can be used in affinity chromatography to purify and isolate glycoproteins, glycolipids, polysaccharides, viruses and cells. Carbohydrate-containing substances bound to the lectin may be eluted with a competitive binding substance.

Genaxxon offers lectins as a freeze-dried powder or as a solution manufactured under aseptic conditions. If you don’t find the lectin you are looking for, we can certainly offer it for you. Just ask us. Furthermore, we offer different custom lectin conjugates on request.

The Genaxxon bioscience lectins are of ultrapure quality and high activity.