FSL-1 FLAG-tag TLR2/TLR6 Agonist

FSL-1 FLAG-tag TLR2/TLR6 Agonist


Order number: P2219.0100

Shipping: shipped at RT, store at -20°C

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

€238.70 *

Weight:

Please select the favoured pack size.

FSL-1 (Pam2CysGDPKHPKSF) showed higher activity than MALP-2 when tested for its capability to... more
Product information "FSL-1 FLAG-tag TLR2/TLR6 Agonist"

FSL-1 (Pam2CysGDPKHPKSF) showed higher activity than MALP-2 when tested for its capability to activate THP-1 cells to produce TNF-alpha and on HEK293 cells transfected with TLR2 and TLR6 to produce NF-kappaB (Okusawa et al. 2004). It was shown that the activity of FSL-1 is TLR2 and TLR6 dependent. A single amino acid substitution from F to R (FSL-2, Pam2Cys-GDPKHPKSR, Cat-No- P2219) > reduced the activity significantly (Okusawa et al. 2004). FSL-1 (P2212) > is more favourable than MALP-2 with respect to solubility in aqueous solutions. FSL-1 is provided as stereochemically defined compounds and as mixture of stereoisomers. Lipopeptides with the S-dihydroxypropyl moiety are not active and therefore suitable as negative controls. Additionally, analogues with different labels or tags are available. Genaxxon offers further analogues differing in the peptide moiety for improved physico-chemical features and high reproducible biological activity. Please inquire for other peptides or more information: info@genaxxon.com.

More products around "FSL-1 FLAG-tag TLR2/TLR6 Agonist"
Specifications: As lipopeptides are very hydrophobic it is most often not possible to purify... more
 

Technical Data:

Specifications:
As lipopeptides are very hydrophobic it is most often not possible to purify them by HPLC. For that reason it is not possible to give purity values (in %) for our standard lipopeptides.
mixture of R,R and R,S stereoisomers
Sequence: Pam2CysGDPKHPKSF

Source

synthetic

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

eclass-Nr: 34-16-04-90
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on FSL-1 FLAG-tag TLR2/TLR6 Agonist. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.