Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL

P2277 - Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL


Order number: P2277.9501

Shipping: Shipment: not cooled. Store at -20°C. For laboratory usage only!
CAS-Nr: 141368-69-6

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

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Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL. T cell epitopes are presented on the surface of... more
Product information "Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL"

Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL. T cell epitopes are presented on the surface of antigen-presenting cells by MHC molecules. T cell epitopes presented by MHC class I molecules are typically peptides between 8 and 11 amino acids in length and exhibiting MHC-specific sequence motifs. These antigenic peptides are derived from non-structural and structural proteins through proteolysis in the cytosolic compartment. Peptide-MHC-I complexes are then transported to the cell surface of antigen presenting cells and are recognised by CD8+ cytotoxic T lymphocytes (CTL). This interaction induces the differentiation of CTLs. Activated CTL lyse the infected cell, secrete cytokines, and proliferate. This mechanism ensures that cells infected by viruses or intracellular bacteria or cancer cells can be detected, since pathogen or cancer-specific MHC peptide complexes are displayed on the cell surface. CTL can recognise such abnormal cells and eliminate them. The genes of MHC I and II molecules are polymorphic. Each MHC allele has a distinct peptide binding motif which favours certain amino acid anchor residues at defined sequence positions. Synonyms for this peptide: Flu MP 58, Influenza Matrix Peptide, Influenza Virus Matrix Protein (58-66), NH2-GILGFVFTL-OH.

More products around "Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL"
Specifications: Purity: >95% (HPLC) Sequence: GILGFVFTL MW = 966.2 g/mol C49H75N9O11... more
 

Technical Data:

Specifications:
Purity: >95% (HPLC)
Sequence: GILGFVFTL
MW = 966.2 g/mol
C49H75N9O11
HLA-type: HLA-A*02:01
lyophilized white powder

Source

synthetic

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

CAS-Nr: 141368-69-6
eclass-Nr: 32-16-04-09
Dokumente - Protokolle - Downloads more


Dokumente - Protokolle - Downloads

Here you will find information and further literature on Influenza A MP (58-66) HLA-A*02:01 GILGFVFTL. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.