RNAi - CRISPR/Cas9

Individual esiRNAs ideal for the functional characterization of single genes. 
esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock. 
esiRNAs targeting transcripts from 1,761 human and 643 mouse non-coding genomic regions.

CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA fragment with homology arms.

Individual   esiRNAs   ideal for the functional characterization of single genes.   esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in... read more »
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RNAi - CRISPR/Cas9

Individual esiRNAs ideal for the functional characterization of single genes. 
esiRNAs targeting transcripts from 16,744 human and 14,068 mouse protein-coding genes in stock. 
esiRNAs targeting transcripts from 1,761 human and 643 mouse non-coding genomic regions.

CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA fragment with homology arms.

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Cas9-Dead-NLS Protein
Cas9-Dead-NLS Protein
The Cas9-Dead-NLS protein is catalytically inactive ("dead") due to the D10A and H840A substitutions. Thus Cas9-Dead-NLS binds to DNA, but does not modify it. This property allows specific genomic targeting, e. g. to block transcription....
From €234.00 *
Cas9-Dead-NLS-EGFP
Cas9-Dead-NLS-EGFP
The Cas9-Dead-NLS-EGFP protein is catalytically inactive ("dead") due to the D10A and H840A substitutions. The NLS is followed by a C-terminal enhanced green-fluorescence protein (EGFP) sequence. The EGFP-tag offers many application...
From €258.00 *
Cas9-Nickase-NLS
Cas9-Nickase-NLS
Cas9-Nickases, mutant forms of the Cas9 protein, only cleave the strand complementary to the gRNA, generating a nick in the double-stranded (ds)DNA. Therefore, Cas9-Nickases need to be complexed with two different gRNAs, targeting...
From €234.00 *
Cas9-NLS (CRISPR associated protein 9)
Cas9-NLS (CRISPR associated protein 9)
The Genaxxon Cas9-NLS represents the wild-type Cas9 nuclease from S. pyogenes , fused with a C-terminal NLS. Currently, the best-established Cas9 protein in the field with most publications. Cas9-NLS (CRISPR associated protein 9) is an...
From €234.00 *
Cas9-NLS-EGFP
Cas9-NLS-EGFP
This innovative Cas9 nuclease is composed of a Cas9 sequence from Streptococcus pyogenes followed by a nuclear-localization sequence (NLS) and a C-terminal enhanced green fluorescent protein (EGFP) tag. Similar to Cas9-NLS-tagRFP > the...
From €258.00 *
Cas9-NLS-tagRFP - Cas9 protein with red fluorescent tag
Cas9-NLS-tagRFP - Cas9 with red fluorescent...
Cas9-NLS-tagRFP is another innovative Cas9 nuclease where the NLS is followed by a C-terminal tag red-fluorescent protein (tagRFP) sequence. The transfection efficiency of Cas9-NLS-tagRFP is as high as for the untagged Cas9-NLS nuclease,...
From €258.00 *
CRISPRfect E transfection reagent - 35µL
CRISPRfect E transfection reagent - 35µL
CrisprFect E transfection reagent is specially designed for use in CRISPR/Cas9 systems. CRISPRfect E is a lipid-based transfection reagent suitable for the delivery of single guide (g)RNA-loaded Cas9 proteins into most adherent cells at...
€144.00 *
esiCRISPR Kit-wt
esiCRISPR Kit-wt
The esiCRISPR Kit applies the CRISPR/Cas9 technology to generate knockouts or knock-ins. For knockouts, no additional components are required. For knock-ins, which are based on homology-directed repair, the user must simply add a DNA...
€550.00 *
esiRNA - Negative Controls
esiRNA - Negative Controls
esiRNA negative controls: - RLUC (Renilla Luciferase) - FLUC (Firefly Luciferase) - EGFP (enhanced green-fluorescent protein) Transfection with these esiRNAs should have no effect, if the corresponding target is not expressed by the...
From €174.00 *
esiRNA - Positive Controls
esiRNA - Positive Controls
Positive controls: - human/mouse Eg5 (KIF11) - Validated esiRNAs. Many common gene targets, including LAMIN A, PLK4, and AURKB, were validated on mRNA and protein level. Transfection with this esiRNA is ideal to optimize the most...
From €174.00 *
GFP-targeting guide RNA for CRISPR
GFP-targeting guide RNA for CRISPR
Purified gRNA, which targets sequences encoding green-fluorescent protein (GFP), or enhanced GFP. This GFP-targeting gRNA may serve as a positive control in down-stream assays, monitoring the success of CRISPR/Cas9 genome editing...
€79.00 *
No target guide RNA for CRISPR experiments
No target guide RNA for CRISPR experiments
No target guide RNA for CRISPR is purified RNA, which has no genomic target in human, rat and mouse. This non-targeting gRNA serves as a tool for establishing non-toxic transfection conditions, or as a negative control in down-stream...
€69.00 *
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